Ex parte SPECK - Page 7




               Appeal No. 95-5133                                                                                                      
               Application 08/135,523                                                                                                  


               such varying results as demonstrated in Tables 1 and 2 of the Schneider declaration.                                    

                       In response to the declaration evidence, the examiner initially (Answer, page 8) states that "the               

               data, taken as a whole, does not clearly provide a basis for concluding non-obviousness."  The                          

               examiner concludes that "the values were not shown to be statistically significant and thus no                          





               different than the control group."  However, the examiner fails to provide any facts or reasons as to why               

               the data is considered to lack statistical significance.  In addition the examiner (Answer, page 9) points              

               to inconsistencies between the first Declaration, originally filed in the parent application, and the second            

               declaration filed in this application.  At page 2 of the Reply Brief, appellant explains these                          

               inconsistencies and urges that the second Declaration provides a more appropriate comparison in that                    

               the side-by-side comparison with a single control provides a more valid comparison.  The examiner                       

               fails to respond to this point in the letter of May 5, 1995.  For many inventions that seem quite obvious,              

               there is no absolute predicatability of success until the invention is reduced to practice.  There is always            

               at least a possibility of unexpected results, that would then provide an objective basis for showing that               

               the invention, although apparently obvious, was in law nonobvious.  In re O’Farrell, 853 F.2d 894,                      

               903, 7 USPQ2d 1673, 1681 (Fed. Cir. 1988).                                                                              

                       On the record before us, we find the evidence presented by appellant is sufficient to overcome                  


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