Ex parte BERSON et al. - Page 9




          Appeal No. 96-2278                                                          
          Application 08/175,001                                                      


          establish a factual basis to support the legal conclusion of                
          obviousness.  See In re Fine, 837 F.2d 1071, 1073, 5 USPQ2d                 
          1596, 1598 (Fed. Cir. 1988).  In so doing, the examiner is                  
          expected to make the factual determinations set forth in                    
          Graham v. John Deere Co.,                                                   
          383 U.S. 1, 17, 148 USPQ 459, 467 (1966), and to provide a                  
          reason why one having ordinary skill in the pertinent art                   
          would have been led to modify the prior art or to combine                   
          prior art references to arrive at the claimed invention.  Such              
          reason must stem from some teaching, suggestion or implication              
          in the prior art as a whole or knowledge generally available                
          to one having ordinary skill in the art.  Uniroyal, Inc. v.                 
          Rudkin-Wiley Corp., 837 F.2d 1044, 1051, 5 USPQ2d 1434, 1438                
          (Fed. Cir.), cert. denied, 488 U.S. 825 (1988); Ashland Oil,                
          Inc. v. Delta Resins & Refractories, Inc., 776 F.2d 281, 293,               
          227 USPQ 657, 664 (Fed. Cir. 1985), cert. denied, 475 U.S.                  
          1017 (1986); ACS Hosp. Sys., Inc. v. Montefiore Hosp., 732                  
          F.2d 1572, 1577, 221 USPQ 929, 933 (Fed. Cir. 1984).  These                 
          showings by the examiner are an essential part of complying                 
          with the burden of presenting a prima facie case of                         
          obviousness.  Note In re Oetiker, 977 F.2d 1443, 1445, 24                   
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