Ex parte HOWARD et al. - Page 3




          Appeal No. 1999-0212                                                        
          Application No. 08/230,526                                                  


          final rejection (Paper No. 19) and the Answer (Paper No. 22)                
          for the reasoning in support of the rejections, and to the                  
          Appellants’ Brief (Paper No. 21), for the arguments                         
          thereagainst.                                                               
               The guidance provided us by our reviewing court for                    
          evaluating the issue of obviousness is as follows:  The                     
          initial burden of establishing a basis for denying                          
          patentability to a claimed invention rests upon the examiner.               
          See In re Piasecki, 745 F.2d 1468, 1472, 223 USPQ 785, 788                  
          (Fed. Cir. 1984).  The question under 35 U.S.C. § 103 is not                
          merely what the references expressly teach but what they would              
          have suggested to one of ordinary skill in the art at the time              
          the invention was made.  See Merck & Co. v. Biocraft Labs.,                 
          Inc., 874 F.2d 804, 807,                                                    
          10 USPQ2d 1843, 1846 (Fed. Cir.), cert. denied, 493 U.S. 975                
          (1989) and In re Keller, 642 F.2d 413, 425, 208 USPQ 871, 881               
          (CCPA 1981).  While there must be some suggestion or                        
          motivation for one of ordinary skill in the art to combine the              
          teachings of references, it is not necessary that such be                   
          found within the four corners of the references themselves; a               


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