Ex parte COLE et al. - Page 3




          Appeal No. 99-0624                                                          
          Application 07/749,482                                                      









                                   THE REJECTIONS                                     
               Claims 112-118, 120-122 and 128-131 stand rejected under               
          35 U.S.C. § 102(b) as being anticipated by Lilly, and under 35              
          U.S.C. § 103 as being obvious over Lilly.                                   
                         Rejection under 35 U.S.C. § 102(b)                           
               In order for a claimed invention to be anticipated under               
          35 U.S.C. § 102(b), all of the elements of the claim must be                
          found in one reference.  See Scripps Clinic & Research Found.               
          v. Genentech Inc., 927 F.2d 1565, 1576, 18 USPQ2d 1001, 1010                
          (Fed. Cir. 1991).                                                           
               The examiner argues that clavulanic acid inherently was                
          produced and isolated by Lilly (answer, pages 3-24).  This                  
          argument is deficient in that it does not address the                       
          limitation in each of the independent claims which requires                 
          that either clavulanic acid (claim 112) or a pharmaceutically               
          acceptable salt thereof (claims 113 and 120) be in combination              

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