Interference No. 103,197 tissue[]" (Page 185, Section 2, first sentence; and Page 197, line 13) would be appropriate. Accordingly, in my opinion, Kapany clearly teaches using any of the probes of figure 7.16 as well as the probes of figure 7.18 for examination of living tissue in general and in particular for oximetry. We agree, up to a point. As noted earlier, the first paragraph of Section 3 ("In Vivo Spectrophotometry") states that "[w]hen the specimen is located subcutaneously, then it is possible to use a fiber optics hypodermic probe in which a rigid fiber bundle is used to illuminate the specimen as well as to return the signal to the detector for [spectrophotometric] processing" (sentence bridging pp. 189- 90). We agree that it would have been obvious to employ any of the hypodermic probe configurations of Figure 7.16 for this purpose, even though they are described only in connection obtaining images for microscopic viewing. Thus, it would have been obvious to use the hypodermic probe apparatus of Figure 7.16(b) or 7.16(c) to perform an invasive spectrophotometric analysis of the tissue between the probe tips by comparing the light that is emitted by one probe with the light that is transmitted through the tissue and received by the other. However, while Kapany broadly suggests invasive transilluminative spectrophotometric analysis of tissue, he - 19 -Page: Previous 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 NextLast modified: November 3, 2007