Interference No. 102,408
no. 1 at Lederle by (CR355):14
[T]reating 945 mg. of 3,3-oxetainedimethanamine in
40 cc of water with 820 mg. of sodium acetate and
2.075 g of potassium tetrachloroplatinate. The
mixture was stirred for three hours and filtered.
The filtered crystals weighed 0.37g; mp 262 dec. and
were labeled “A”. The filtrate was allowed to stand
overnight and then the resulting solid was collected
giving 440 mg of product as bright yellow crystals
melting at 270-272E which was labeled “B”.
Compare CR365 (product labeled "A" described as beige solid
having melting point of 262E; product "B" described as bright
yellow crystals having melting point of 270-273E). Products
labeled “C”, “D” and “E” also appear to have been prepared
during the process (CR365).
Various notations have been used throughout the record to
identify products which appear to be described on page 47 of
notebook 12459B. For example, a request for infrared analysis
prepared by Ralph G. Child uses the notation "sample no.
12459B-47B" to identify one such compound. See CR356, ¶ 4; 15
14American Cyanamid Company, Lederle Laboratories
Division, Pearl River, New York, USA (hereinafter "Lederle").
15Presumably, the notation "12459B-47B" is intended to
identify the product labeled "B" on page 47 of Child's
notebook 12459B, the preparation of which is described
therein. Compare CR365 (product "B" described as "bright
yellow crystals wt=0.44 mp 270-273E") with CR366
("[Stru]cture, Color and State [:] yellow crystals [;] BP or
12
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