Interference No. 102,408
declaration of Stanley A. Lang, the Head of the Chemistry
Department of the Infectious and Neoplastic Disease Research
Section at Lederle from 1980-1990. According to Lang, Yang-I
Lin, Ralph G. Child, Panayota Bitha and Joseph Hlavka, the
inventors in the Child application involved in this
interference, would prepare and submit monthly reports to Lang
(CR218, ¶ 2). Lang would review these reports and use the
information to prepare a monthly summary which would be
integrated into a monthly report for the Infectious and
Neoplastic Disease Section (CR218-19, ¶¶ 3-4). The summary
for August 1984 reads in part as follows (CR223):
Chemistry (Bitha, Child, Hlavka, Lin, and Sliskovic)
As a continuation of our work reported last month on
the synthesis of 3,3-bisaminomethyloxetane platinum
complexes, dichloro(3,3-bisaminomethyloxetane)
platinum complex 1a reacted with a series of acids
by the silver nitrate process to give the following
complexes 1b-g. The water soluble complex 1h (water
solubility = 3.5 mg/ml) showed good activity over a
wide dose range; i.e., T/C x 100 of 253 at 50 mg/kg
and 136 at 3.1 mg/kg.
Issues (1), (6) and (7)
Based on the record before us, junior party Child has
failed to establish an actual reduction to practice of the
subject matter of the count prior to September 3, 1984,
Kolar's effective filing date. An actual reduction to
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