NEMERSON et al. V. EDGINGTON et al. V. LAWN et al. - Page 16


                Interference No. 103,203                                                                                                      

                count of the involved ‘989 Application are not enabled because the specification fails to                                     
                disclose whether clone 8TF14 and vectors pCIS2.8c26D, pCIS2.CXXNH and pCIS.TF                                                 
                                                     8                                                                                        
                were appropriately deposited,  we point out that not one of Lawn et al.’s claims                                              
                corresponding to the count requires the use of the referenced clone and vectors.  Thus, this                                  
                argument does not address a limitation present in the claims.  In addition, enablement                                        
                does not require that the specification disclose that which is well known in the art.                                         
                Hybritech Inc. v. Monoclonal Antibodies, Inc., 802 F.2d 1367, 1385, 231 USPQ 81, 94                                           
                (Fed. Cir. 1986), cert. denied, 480 U.S. 947 (1987).  Here, the Lawn et al. application                                       
                states that there are numerous eucaryotic and procaryotic expression vectors known in the                                     
                art.  See, e.g., the ‘989 Application, pp. 22-23.  Accordingly, absent evidence to the                                        
                contrary, we find that those skilled in the art would have understood that any vector known                                   
                in the art at the time the application was filed could have been employed to express the                                      
                human tissue factor DNA sequences disclosed therein.                                                                          




                         As to Edgington et al.’s arguments with respect to the description of the signal                                     
                sequence peptide and the starting material for the cDNA library in the ‘989 Application,9                                     
                we again point out that said application discloses the complete and correct nucleotide                                        
                sequence of the human tissue factor protein.  See, e.g., Figure 2 of the ‘989 Application.                                    
                Absent evidence to the contrary, we find that the disclosure of said nucleotide sequence is                                   



                         8Paper No. 167, pp. 4-7.                                                                                             
                         Paper No. 167, p. 4 (para. 7) and p. 7 (para. 18).9                                                                                                                   
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