Interference No. 103,586
____________
Before DOWNEY, WILLIAM F. SMITH and LORIN, Administrative Patent Judges.
DOWNEY, Administrative Patent Judge.
This interference involves a patent to Barbacid et al. (Barbacid), U.S. Patent No.
5,185,248, assigned to E.R. Squibb and Sons, Inc., (a subsidiary of Bristol-Myers Squibb
Co.) (hereinafter Squibb), and an application to Brown et al.(Brown), Serial No.
07/937,893, assigned to Board of Regents, University of Texas System, with Genentech,
Inc., as non-exclusive licensee of the subject matter of this application.
The subject matter at issue is an assay for identifying a candidate/test substance
having the ability to inhibit a farnesyl transferase enzyme. The subject matter at issue is
defined by a single count, which count is a bifurcated count which includes Barbacid’s
patent claim 1 and Brown’s claim 37. The count reads as follows:
Count 1
A method for identifying a candidate substance having the ability to inhibit a farnesyl
transferase enzyme, comprising the steps of:
(a) obtaining an enzyme composition comprising a farnesyl transferase enzyme that
is capable of transferring a farnesyl moiety to a farnesyl acceptor substance;
(b) admixing a candidate substance with the enzyme composition and farnesyl
pyrophosphate; and
(c) determining the ability of the farnesyl transferase enzyme to transfer a farnesyl
moiety to a farnesyl acceptor substrate in the presence of the candidate substance and in
the absence of the candidate substance
-2-
Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Next
Last modified: November 3, 2007