Ex parte DICK et al. - Page 16




              Appeal No. 1995-2297                                                                                           
              Application No. 07/797,493                                                                                     



              drawn to a “stable bone marrow graft of lineage-specific human hematopoietic cells” is                         
              unclear.                                                                                                       
                      The examiner simply states “that it would have been obvious and well within the skill                  
              of the art to select or assay for human growth factors which would be suitable for                             
              administration to a chimeric mouse in order to obtain enhanced engraftment and                                 
              differentiation of human hematopoietic cells.”  See, e.g., Answer, page 9.  The examiner                       
              concludes, “not all the claims recite the argued property.  Thus, [a]ppellants’ argument is                    
              not commensurate with the scope of the claims and is thus not persuasive.”  The                                
              examiner’s statements are not sufficient.                                                                      
                      A rejection under 35 U.S.C. § 103 requires that obviousness be determined based                        
              on the claimed subject matter as a whole.  Only when the prior art suggests the subject                        
              matter of a claim as a whole, and provides an enabling disclosure as to how one would                          
              make the claimed invention, can one properly conclude that the subject matter of a claim                       
              would have been obvious under 35 U.S.C. § 103.                                                                 
                      The examiner erred in considering the patentability of claims 13 and 14 under                          
              35 U.S.C. § 103 without first “having ascertained exactly what subject matter is being                         
              claimed.”  In re Wilder, 429 F.2d at 447, 450, 166 USPQ 545, 548 (CCPA 1970).                                  


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