Ex parte DICK et al. - Page 11




                   Appeal No. 1995-2297                                                                                                                             
                   Application No. 07/797,493                                                                                                                       



                   of mouse origin, and human cells account for only approximately 0.3 to 3.0% of the bone                                                          
                   marrow in Kamel.  See, Brief, pages 6 and 10.  Appellants contrast the prior art with the                                                        
                   bone marrow of their mice in which at least 30% of the cells are of human origin.  See,                                                          
                   Brief, pages 6 and 10.   We affirm the examiner with regards to claims 4 and 6-8, and                                                            
                                                                                                             2                                                      
                   reverse the examiner’s rejection as it applies to claims 1 and 2.                                                                                
                            “Where a product-by-process claim is rejected over a prior art product that                                                             
                   appears to be identical, although produced by a different process, the burden is upon the                                                        
                   applicants to come forward with evidence establishing an unobvious difference between                                                            
                   the claimed product and the prior art product.  In re Best, 562 F.2d [1252,] 1255, 195                                                           
                   USPQ [430,] 433[ (CCPA 1977)].”  In re Marosi, 710 F.2d 799, 803,                                                                                
                   218 USPQ 289, 292-93 (Fed. Cir. 1983).                                                                                                           
                            Appellants demonstrate that the bone marrow is comprised of at least 30% human                                                          
                   origin.  However, as the examiner notes, this distinction over the prior art is not                                                              




                   2We recognize appellant’s request that claims 1, 2, 4 and 6-8 stand or fall together,                                                            
                   however, upon review of this record, we have determined that claims 1 and 2 can be                                                               
                   properly distinguished from claims 4 and 6-8.  Therefore, we have considered claims 1                                                            
                   and 2 separate from claims 4 and 6-8.                                                                                                            


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