Ex parte DICK et al. - Page 4




              Appeal No. 1995-2297                                                                                        
              Application No. 07/797,493                                                                                  



              Kamel-Reid et al. (Kamel), “Engraftment of Immune-Deficient Mice with Human                                 
              Hematopoietic Stem Cells” 242 Science, pp. 1706-09 (1988)                                                   
              Lubin et al. (Lubin), “Engraftment and Development of Human T and B Cells in Mice After                     
              Bone Marrow Transplantation” 252 Science, pp. 427-31 (1991)                                                 

                                      GROUNDS OF REJECTION ON APPEAL                                                      
                     Claims 1, 2, 4, 6-9 and 11-14 are rejected under 35 U.S.C. § 103.  As evidence of                    
              obviousness, the examiner relies upon any one of Pollard, Wade or Fohlmeister taken with                    
              McCune.                                                                                                     
                     Claims 1, 2, 4, 6-9 and 11-14 are rejected under 35 U.S.C. § 103.  As evidence of                    
              obviousness, the examiner relies upon Reisner, Lubin or Kamel.                                              
                     We reverse the rejection of claims 1, 2, 4, 6-9 and 11-14 under 35 U.S.C. § 103                      
              over  Pollard, Wade or Fohlmeister taken with McCune.  For reasons discussed herein, we                     
              consider claims 1 and 2 separately from claims 4 and 6-8.  We affirm the rejection of                       
              claims 4 and 6-8 under 35 U.S.C. § 103 over Reisner, Lubin, or Kamel.  We reverse the                       
              rejection of claims 1, 2, 9, 11 and 12 under 35 U.S.C. § 103 over Reisner, Lubin or Kamel.                  
              We vacate the rejection of claims 13 and 14 under 35 U.S.C. § 103                                           





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