Appeal No. 1995-2297 Application No. 07/797,493 Kamel-Reid et al. (Kamel), “Engraftment of Immune-Deficient Mice with Human Hematopoietic Stem Cells” 242 Science, pp. 1706-09 (1988) Lubin et al. (Lubin), “Engraftment and Development of Human T and B Cells in Mice After Bone Marrow Transplantation” 252 Science, pp. 427-31 (1991) GROUNDS OF REJECTION ON APPEAL Claims 1, 2, 4, 6-9 and 11-14 are rejected under 35 U.S.C. § 103. As evidence of obviousness, the examiner relies upon any one of Pollard, Wade or Fohlmeister taken with McCune. Claims 1, 2, 4, 6-9 and 11-14 are rejected under 35 U.S.C. § 103. As evidence of obviousness, the examiner relies upon Reisner, Lubin or Kamel. We reverse the rejection of claims 1, 2, 4, 6-9 and 11-14 under 35 U.S.C. § 103 over Pollard, Wade or Fohlmeister taken with McCune. For reasons discussed herein, we consider claims 1 and 2 separately from claims 4 and 6-8. We affirm the rejection of claims 4 and 6-8 under 35 U.S.C. § 103 over Reisner, Lubin, or Kamel. We reverse the rejection of claims 1, 2, 9, 11 and 12 under 35 U.S.C. § 103 over Reisner, Lubin or Kamel. We vacate the rejection of claims 13 and 14 under 35 U.S.C. § 103 4Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007