Appeal No. 1996-0682
Application 08/127,121
claims in the application. As evident from representative
appealed claim
25 reproduced below, the subject matter on appeal is directed
to an acidic pharmaceutical cream preparation containing the
active ingredient, podophyllotoxin, and between 3 and 15
weight percent of fractionated coconut oil triglyceride.
25. A pharmaceutical cream preparation, consisting
essentially of:
an effective amount of podophyllotoxin for treating
psoriasis or condyloma acuminata, and between 3 and 15
weight percent of a medium chain length liquid
triglyceride which is a fractionated coconut oil;
wherein the cream preparation is prepared by
suspending the podophyllotoxin in the liquid triglyceride
to form a fatty phase, and then emulsifying the fatty
phase with an aqueous phase; and
wherein the pharmaceutical cream preparation
possesses a pH value of between 2 and 6.
Prior art references relied upon by the examiner as
evidence of obviousness are:
Evers 4,235,889 Nov. 25,
1980
Jacobsen et al. (Jacobsen) 0,119,852 Sep. 26,
1984
European Patent Application
Leander et al. (Leander) 4,788,216 Nov.
29, 1988
Makino et al. (Makino) 4,789,667 Dec. 6,
1988
2
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