Ex parte JONES - Page 4




              Appeal No. 1996-0848                                                                                        
              Application 07/624,053                                                                                      




                     The reference relied upon by the examiner is:                                                        
              Jones et al. (Jones), "Monocyte Cytotoxicity Factor (MCF) Production by Human T-cell                        
              Hybridoma," Immunobiol., vol. 167, abstract no. 365 (1984).                                                 
                                                 Grounds of Rejection                                                     

                    Claims 16-22, 24-25, 27-32, 34-35, and 42 stand rejected under 35 U.S.C. § 112, first                 
            paragraph, as being based on a non-enabling disclosure.                                                       
                    Claims 16-22, 24-25, 27-32, 34-35, and 42 stand rejected under 35 U.S.C. § 112,                       
            second paragraph, as failing to particularly point out and distinctly claim the invention.                    
                    Claims 16-22, 24-25, 27-32, 34-35, and 42 stand rejected under 35 U.S.C. § 102 (b).                   
            As evidence of anticipation, the examiner relies upon Jones.                                                  
                    We reverse.                                                                                           
                                                     Background                                                           

                     The applicant describes the invention, as presently claimed, at page 9 of the                        
              specification as being directed to a continuous cell line, as well as a method of generating                
              a continuous cell line, which produces a human monocyte cytotoxicity inducing factor                        
              (MCF) that is capable of inducing human monocytes to a cytotoxic state, wherein the cell                    
              line is produced by a process which includes the steps of immortalizing human T-cells to                    
              produce continuous cell clones, identifying a clone which produces the factor, and culturing                
              the clone to provide the continuous cell line.                                                              

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