Ex Parte WEIDLE et al - Page 4




              Appeal No. 1996-1002                                                                                     
              Application 07/988,945                                                                                   


                                                   BACKGROUND                                                          
                     The invention is described at page 3 of the specification as being directed to an                 
              antibody composition which inhibits the binding of interleukin 2 to its high affinity                    
              receptor.  The composition is described as a combination comprising a monoclonal                         
              antibody against the " chain of the interleukin 2 receptor (IK-2R") and a monoclonal                     
              antibody against the interleukin 2 receptor $ chain (IK-2R$) of the interleukin 2                        
              receptor.  The use, in combination, of monoclonal antibodies against the "-chain and                     
              the $-chain of the IL-2 receptor is said to lead to a synergistic effect resulting in a                  
              stronger inhibition of the IL-2 induced proliferation of human peripheral blood                          
              lymphocytes.                                                                                             
                                                    DISCUSSION                                                         
                              The rejection under 35 U.S.C. § 112, second paragraph                                    
                     The examiner has rejected claim 27 based on the presence, therein, of the term                    
              "humanized" which the examiner urges is ambiguous.  We point out that it is well                         
              established that "definiteness of the language employed must be analyzed, not in a                       
              vacuum, but always in light of the prior art and of the particular application disclosure as             
              it would be interpreted by one possessing the ordinary level of skill in the pertinent art."             
              In re Moore, 439 F.2d 1232, 1235, 169 USPQ 236, 238 (CCPA 1971).  Here, both the                         
              examiner (Answer, page 14) and appellants (Brief, page 10) agree that the term                           
              "humanized", used in the context of claim 27, is an art recognized term and that                         

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