Ex parte WANG - Page 4




                Appeal No. 1997-0094                                                                                                           
                Application No. 08/188,232                                                                                                     


                         In reaching our decision in this appeal we have given careful consideration to the                                    
                appellant's specification and claims and to the respective positions articulated by the                                        
                appellant and the examiner.  We make reference to the examiner's answer (Paper No. 17,                                         
                mailed May 14, 1996) and to the examiner's supplemental answer (Paper No. 20, mailed                                           
                October 15, 1996) for the examiner's reasoning in support of the rejection and to the                                          
                appellant's brief (Paper No. 16, filed December 4, 1995), to the appellant's reply brief                                       
                (Paper No. 19, filed July 12, 1996) and to the appellant's second reply brief (Paper No. 21,                                   
                filed December 16, 1996) for the appellant's arguments thereagainst.                                                           
                                                             BACKGROUND                                                                        
                         Prothymosin ",  a native thymic polypeptide isolated from thymosin fraction 5, is the                                 
                precursor from which a number of biologically active peptides, including thymosin "  and                                       
                                                                                                                        1                      
                two related peptides, des-(25-28)-thymosin "  and thymosin " , are derived.  Thymosin1                   11                                               
                "  is defined by the first 28 amino acid residues of the N-terminal of prothymosin "; des-                                     
                  1                                                                                                                            
                (25-28)-thymosin "  by the first 24 amino acid residues; and, thymosin "  by the1                                                              11                                  
                sequence of thymosin "  plus seven additional residues at the COOH terminus.  See                                              
                                              1                                                                                                
                Haritos, p. 1008, c. 1 and Zatz, Table I.                                                                                      








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