Appeal No. 1997-1280 Page 6 Application No. 08/356,912 Appellants have asserted that there is a showing of unexpected properties in the Declarations of record. We determine that the argument is unpersuasive, because the species utilized in the Declaration, N-[2,3-dihydro-2-(1-pyrrolidinyl)-1H-inden-1-yl]-3,4- dimethoxy-N-methyl-benzene- acetamide, representative of the prior art, is not prepared by Pennev. Moreover, Pennev clearly teaches another species, N-[2,3-dihydro-2-(1- pyrrolidinyl)-1H-inden-1-yl]-3,4-dichloro-N-methyl-benzene- acetamide within the scope of the claimed subject matter other than for the presence of the 3,4-dichloro groups. See Example 6. We determine that Example 6 is the closest example to the claimed subject matter. Moreover, the compound of Example 6, is also one of the appellants preferred, but unclaimed compounds. See specification, page 5, lines 6-8. Hence, the comparative examples which fail to include that compound do not reflect the closest prior art relied upon in our opinion. In re Baxter Travenol Labs., 952 F.2d 388, 392, 21 USPQ2d 1281, 1285 (Fed. Cir. 1991); In re De Blauwe, 736 F.2d 699, 705, 222 USPQ 191, 196 (Fed. Cir. 1984). In addition, it is well settled that direct or indirect testing between the claimed compounds and the closest prior art may be necessary. In re Merchant 575 F.2d 865, 869, 197 USPQ 785, 788 (CCPA 1978). Furthermore, each of the tests conducted by declarant Fortin, uses the same single species of prior art compound. i.e., N-[2,3-dihydro-2-(1-pyrrolidinyl)-1H-inden-1-yl]-3,4- dichloro-N-methyl-benzene- acetamide. It is well settled that, “where an applicant tests lessPage: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007