Appeal No. 1997-1301 Application No. 08/079,310 The examiner has not presented any convincing evidence or reasoning as to why the proposed substitution at the alpha carbon of the benzyl group would facilitate the reaction set forth in Scheme III of Reichmanis. The heterocyclic intermediate in Scheme III of Reichmanis is formed by removal of a hydrogen atom from the alpha carbon of the benzyl group (page 398). The examiner has not explained or presented reasoning why an electron-withdrawing group would not make removal of this hydrogen more difficult, rather than facilitate its removal (see the Reply Brief, page 10). For the foregoing reasons and those presented in the Reply Brief, we determine that the examiner has not established a prima facie case of obviousness. In light of this determination, we need not consider the sufficiency of appellants’ evidence of unobviousness (e.g., the Houlihan Declaration under 37 CFR § 1.132 dated Jan. 13, 1997, Paper No. 22). In re Geiger, 815 F.2d 686, 688, 2 USPQ2d 1276, 1278 (Fed. Cir. 1987). Accordingly, the examiner’s rejection of claims 1-5 under 35 U.S.C. § 103 as unpatentable over Houlihan in view of 11Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007