Ex parte YAGIHASHI et al. - Page 4




          Appeal No. 1997-2270                                                        
          Application 08/294,214                                                      


               JP ‘473 discloses fused lactones wherein a group can be                
          either hydroxyl or a protected hydroxyl, and discloses a                    
          method for protecting the hydroxyl groups of the fused                      
          lactones (pages 2 and 15).                                                  
               The examiner argues that “[i]t would have been prima                   
          facie obvious at the time the claimed invention was made to                 
          protect the hydroxy groups of the prior art by using the                    
          conventional hydroxy groups as taught by Japanese patent J 02-              
          311473 and Greene et al. to form the protected prior art                    
          compounds without the loss of the same activity” (answer, page              
          3).  For the following reasons, the examiner’s argument is not              
          persuasive.                                                                 
               First, as argued by appellants (brief, pages 4-5), the                 
          examiner has not explained why the applied prior art would                  
          have motivated one of ordinary skill in the art to use                      
          protecting groups for the hydroxyl groups of the prior art                  
          bisphenol derivative.  Appellants argue that the fused                      
          lactones of JP ‘473 are not structurally similar to                         
          appellants’ claimed compound (brief, page 5), and the examiner              
          does not challenge this argument.  Also, the examiner has not               
          established that the mere knowledge that the protecting groups              
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