Ex parte BECHER et al. - Page 11




              Appeal No. 1997-2336                                                                                          
              Application No. 08/256,065                                                                                    
              sufficient to meet the burden of demonstrating that the disclosure is enabling.  The                          
              examiner has established a prima facie case of lack of enablement which is sufficient to                      
              support the rejections of claims 27-35 under 35 U.S.C. § 112, first paragraph, which                          
              appellants have not overcome by arguments or convincing evidence.  Therefore, the                             
              rejection of claims 27-35 under 35 U.S.C. § 112, first paragraph, is affirmed.                                
              Claim 36:                                                                                                     

                     We vacate the rejection of claim 36 under 35 U.S.C. § 112, first paragraph, as                         
              being based on a non-enabling disclosure for the following reasons.  The record with                          
              regard to this claim is less than clear.  Claim 36 is directed to a therapeutic method                        
              wherein the tumor prophylaxis is against tumor formation in the gastrointestinal tract.  The                  
              appellants in their principal Appeal Brief at page 6 state that claims 27-36 are grouped                      
              together which is reasonably read as indicating that they stand and fall together. (37 CFR §                  
              1.192(7)(1995)).  Yet, in the Reply Brief of November 8, 1996 (Paper No. 18) at pages 1-                      
              2, appellants separately argue claim 36 as being limited to the use of aspirin against tumor                  
              formation in the gastrointestinal tract which reads on the use of aspirin to prevent colon                    
              cancer.  The examiner acknowledged receipt and entry of the Reply Brief in a letter mailed                    
              November 26, 1996 (Paper No. 20),but failed to respond to the newly submitted                                 
              arguments relating to claim 36.  Thus, we are left with no rebuttal to arguments explicitly                   
              raised by the appellants and no indication whether these arguments taken with the                             
              teaching of the Thun I would reasonably be considered persuasive.  In this regard, we note                    


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