Appeal No. 1997-2338 Application No. 08/173,376 Only if that burden is met, does the burden of coming forward with evidence or argument shift to the applicants. Id. In order to meet that burden the examiner must provide a reason, based on the prior art, or knowledge generally available in the art as to why it would have been obvious to one of ordinary skill in the art to arrive at the claimed invention. Ashland Oil, Inc. v. Delta Resins & Refractories, Inc., 776 F.2d 281, 297, n.24, 227 USPQ 657, 667, n.24 (Fed. Cir. 1985,. cert. denied, 475 U.S. 1017 (1986). On the record before us, the evidence provided by the examiner in support of this rejection fails to support a conclusion that it would have been obvious to one of ordinary skill in this art to prevent insects from biting vertebrate species in the manner presently claimed. As we have interpreted claim 6, the method consists essentially of topically applying a pesticide composition to a surface of a vertebrate wherein the composition consists essentially of a water swellable polycarboxylated homopolymer or copolymer and an effective amount of a pesticide in a volatile non-aqueous solvent, drying the applied composition to form a surface adherent non-aqueous film of the polymer and pesticide on the vertebrae surface and then contacting the dried film with water to swell the film and promote the release of the pesticide from the film. Appellant acknowledges that Chromecek and Amidon (Brief, page 4): teach the use of carboxylated polymers in carrier systems for bioactive agents. Chromecek describes carboxylated polymer carriers wherein the hydrophilic functional groups of the polymers are complexed to aluminum, zinc or zirconium. The Amidon et al. reference is directed to polymer compositions and a method of applying the compositions to a surface. Amidon=s method comprises the steps of applying a low viscosity hydrophilic 7Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007