Ex parte GOLDENBERG - Page 7




             Appeal No. 1997-2368                                                                                 
             Application 08/158,782                                                                               


             however, simply to engage in a hindsight reconstruction of the claimed invention using               
             applicants' specification as a template and selecting elements from references to fill the           
             gaps.  In re Gorman,                                                                                 
             933 F.2d 982, 986-87, 18 USPQ2d 1885, 1888 (Fed. Cir. 1991).  Thus, we find that the                 
             examiner has not provided the factual evidence which would reasonably support a                      
             rejection of the claims on appeal under 35 U.S.C. § 103.                                             
                    Where, as here, the examiner fails to establish a prima facie case of obviousness,            
             the rejection is improper and will be overturned.  In re Fine, 837 F.2d 1071, 1074, 5                
             USPQ2d 1596, 1598 (Fed. Cir.1988).  Therefore the rejection of claims 1, 3-6, 8-10, 19,              
             20, 24, 25, 39-44, and 46-48 under 35 U.S.C. § 103 is reversed.                                      
                                       Obviousness-type Double Patenting                                          
                    Claims 1, 3-6, 8-10, 19, 20, 24, 25, 39-44, and 46-48 stand rejected under the                
             judicially created doctrine of obviousness-type double patenting over claims 1-29 of U.S.            
             Patent No. 5,332,567.  In setting forth the reasoning in support of this rejection, the              
             examiner recognizes that the claims on appeal are directed to a therapeutic treatment                
             wherein a patient is injected with “an effective amount” of a therapeutic agent while the            
             claims of U.S. Patent No. 5,322,567 are directed to a diagnostic method wherein the                  
             patient is injected with “an effective amount” of a diagnostic agent. (Answer, page 7).              
             Without further explanation, the examiner concludes the “the differences fail to provide any         


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