Appeal No. 1997-2829 Application No. 08/456,090 the dosage, e.g., the amount, frequency and duration of baclofen required to suppress coughing, such as that induced by ACE inhibitors. (If a headache persists after administering a single dosage of aspirin, more aspirin is usually taken until the headache is gone.) The rejection of claims 1-6 under 35 U.S.C. § 103 over Kreutner is affirmed. 4. Appellant argues that claim 13 is patentable for the following reasons: a. Claim 13 recites administering from 10 to 30 mg daily of baclofen for about three days to suppress the cough associated with the administration of an ACE inhibitor; and b. The Rule 132 Declaration provides evidence that baclofen has no effect on ACE inhibitor induced coughing until three days have elapsed. See Brief, Paper No. 10, paragraph bridging pages 4 and 5. However, as set forth in section VI-B2, supra, Kreutner discloses that baclofen can be administered from 5 to 5000 mg/day, preferably from 10 to 1000 mg/day, to achieve relief of cough (Kreutner, col. 3, lines 53-57). Appellant at page 3, lines 21-23 of the Brief, acknowledges that this "embraces" -15-Page: Previous 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 NextLast modified: November 3, 2007