Appeal 1997-3391 Application 08/212,578 effects, either for prior art flupirtine compounds or pharmaceutical compositions with the scope of the invention. 13. Thus, on this record all we have is applicants' assertion that side effects are reduced when the compositions of claim 1 are used as an analgesic. The examiner's rejection 14. A final rejection was withdrawn in the Examiner's Answer, where a new ground of rejection was entered (Examiner's Answer, page 3). 15. The examiner has rejected claims 1-7 as being unpatentable under 35 U.S.C. § 103 over Lobisch, U.S. Patent 5,162,346 (1992), Tamás, U.S. Patent 4,748,023 (1988) and Eichel, U.S. Patent 5,238,686 (1993). 16. Applicants timely filed a reply brief responding to the examiner's new ground of rejection. 17. There was no further response by the examiner. Lobisch 18. Lobisch reveals that flupirtine "is an analgesic, i.e., it causes an insensibility to pain without anesthesia or loss of consciousness" (col. 1, lines 11-15). 19. In fact, flupirtine is said to have "a pronounced analgesic effect" (col. 2, lines 23-24). 20. According to Lobisch (col. 2, lines 1-6): - 4 -Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007