Ex parte PEYMAN - Page 9




          Appeal No. 1998-0308                                                        
          Application 07/844,879                                                      


               Peyman describes an unsuccessful experiment to modify the              
          curvature of rabbit corneas by using a carbon dioxide laser to              
          produce burns of various intensities, locations and patterns                
          on the front corneal surface.                                               


               The foregoing references constitute a disparate lot in                 
          terms of the various eye surgery methods taught or suggested                
          thereby.  The non-invasive laser techniques disclosed by                    
          L’Esperance ‘608 and L’Esperance ‘913, the cataract ablation                
          procedure disclosed by Bath and the rabbit experiment                       
          described by Peyman have little, if any, reasonable pertinence              
          to the lamellar corneal stromectomy technique disclosed by                  
          Krwawicz.  Although the invasive laser probe disclosed by                   
          L’Esperance ‘541 is described as having general utility for                 
          the vaporization and removal of corneal tissue, there is                    
          nothing in this reference which indicates that the probe might              
          be effective for, or even capable of, the particular corneal                
          tissue removal step in the Krwawicz process.  Against this                  
          backdrop, the appellant’s position that the reference                       
          combinations advanced by the examiner are predicated on                     
          impermissible hindsight is persuasive.  Given the                           
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