JEON et al. V. CUPPS et al. - Page 18




          Interference No. 104,241                                                    



               Additionally, in establishing an actual reduction to                   
          practice, each of the prerequisites for establishing an actual              
          reduction to practice must be corroborated by a non-inventor.               
          The objective sought in requiring independent corroboration of              
          an actual reduction to practice of a chemical compound is to                
          insure that the inventor actually prepared the compound and                 
          knew it would work for its intended purpose.  However, the                  
          standard is not inflexible and is not to be applied                         
          mechanically.  Hence a "rule of reason" approach is required.               
          Mikus v. Wachtel, 504 F.2d 1150, 1152, 183 USPQ 752, 753 (CCPA              
          1974).  Further, corroboration does not necessarily have to be              
          established by an "over-the-shoulder" observer.  Rather,                    
          sufficient circumstantial evidence can satisfy the requirement              
          for corroboration. Knorr v. Pearson, 671 F.2d 1368, 1373, 213               
          USPQ 196, 200 (CCPA 1982); Lacotte v. Thomas, 758 F.2d 611,                 
          613, 225 USPQ 633, 634 (Fed. Cir. 1985); Berges v. Gottstein,               
          618 F.2d 771, 774, 205 USPQ 691, 695 (CCPA 1980).                           
          Nonetheless, each and every limitation or element of the count              
          must be corroborated.  Mikus v. Wachtel, id.                                
               Where, as here, the count embraces a broad genus of                    
          compounds, the reduction to practice of a single compound                   

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