Ex parte PISHEVAR - Page 8


                 Appeal No.  2000-1919                                                                                   
                 Application No. 08/831,993                                                                              

                 Marzocchi, 439 F.2d at 223, 169 USPQ at 369, emphasis in original.  The                                 
                 examiner’s complaints about the data in this case do not provide a sufficient                           
                 basis “to doubt the objective truth of the statements” in the specification.                            
                        Appellant’s position is also supported by the Ludtke declaration.  Dr.                           
                 Ludtke declares that “the application teaches in detail everything one of ordinary                      
                 skill in the art needs to practice the invention (i.e. inhibit the development of                       
                 intracellular parasites in erythrocytes) without the need for any experimentation                       
                 beyond routine screening.”  Ludtke declaration, paragraph 2.  The examiner has                          
                 cited no evidence that contradicts the Ludtke declaration.  Rather, he dismissed it                     
                 as “not provid[ing] any further factual evidence and merely cit[ing] the                                
                 specification.”  Examiner’s Answer, page 8.  Therefore, as Appellant notes, the                         
                 Ludtke declaration remains  uncontroverted as evidence that the claims are fully                        
                 enabled by the specification.  Reply Brief, page 1.                                                     
                        With respect to the PGLa and XPF peptides encompassed by claims 1                                
                 and 11, Appellant argues that “[t]he use of PGLa and XPF peptides is the same                           
                 as the structurally analogous magainin peptides. . . .  Substituting one taught                         
                 peptide for another taught peptide does not require undue experimentation.”                             
                 Revised Appeal Brief, page 4.  The examiner provided no substantive response                            
                 (see the Examiner’s Answer, page 8) and no evidence or reasoning on which to                            
                 base a conclusion that using PGLa or XPF peptides in the claimed method would                           
                 require undue experimentation.  We therefore conclude that the examiner has                             
                 not met his burden of showing nonenablement with respect to this limitation.                            



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