Ex parte BARENHOLZ et al. - Page 4




                Appeal No. 1997-1913                                                                                                           
                Application 08/238,149                                                                                                         

                components of PC in the heart cells of the subject at a younger age."  The specification                                       
                states at page 9, lines 13-17, that the acyl chain length and the degree of acyl chain                                         
                saturation increase with age.  The administration is repeated "over a period of at least                                       
                several days" until there is a significant drop in the serum creatinine phosphokinase level of                                 
                the subject.  Guidance as to the dosage and timing of the administration is provided in the                                    
                specification at pages 13-14 and 19-20.                                                                                        
                                                              DISCUSSION                                                                       
                         Claims 23-25 stand rejected under 35 U.S.C. ?  103(a) over Williams in combination                                    

                with Taylor.  The examiner bears the initial burden of establishing a prima facie case of                                      
                obviousness under 35 U.S.C. ?  103.  In re Warner, 154 USPQ 173, 177 (CCPA 1967).  In                                          

                so doing, he or she must consider every limitation of the claimed invention.  See In re                                        
                Royka, 490 F.2d 981, 180 USPQ 580, 582-83 (CCPA 1974); In re Wilson, 165 USPQ                                                  
                494, 496 (CCPA 1970) ("All words in a claim must be considered in judging the                                                  
                patentability of that claim against the prior art").                                                                           
                         Claim 23 requires that the PC employed have "an acyl chain composition which is                                       
                characteristic, at least with respect to transition temperature, of the acyl chain components                                  
                of PC in the heart cells of the subject at a younger age."  According to the specification                                     
                (see page 9, lines 13-17), both the acyl chain length and the degree of acyl chain saturation                                  
                increase with age.  Thus, we agree with appellants that the requirements of claim 23 are                                       



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