Ex parte SPELMAN et al. - Page 8




          Appeal No. 1997-2245                                       Page 8           
          Application No. 08/402,872                                                  


          suggestion in the prior art to make the modification proposed               
          by the examiner.                                                            
               From our review of the collective teachings of Mishin,                 
          Weitschies, Macri, and Leibing, we are in agreement with                    
          appellants that the suggestion of replacing the magnetic field              
          strength measuring devices of Mishin, Weitschies, or Macri                  
          with a compass comes from appellants' disclosure.  In each of               
          Mishin, Weitschies, and Macri gut motility is measured.                     
               In Mishin (pages 1 and 2), a mixture including finely                  
          dispersed magnetic particles is ingested.  Pairs of induction               
          coils are placed around the patient, and the velocity of the                
          advance of the magnetic particles is recorded on the basis of               
          the electromotive force induced in the magnetic induction                   
          coils.                                                                      
               In Weitschies (page 191, col. 2 and page 193, col. 1),                 
          magnetic markers in the form of magnetite coated pellets are                
          ingested.  A seven channel SQUID device was used for                        
          measurement of weak magnetic fields (page 193, col. 2, and                  
          page 192, col. 1) as the ingested markers move through the                  
          gut.  Because slight changes in the orientation of the marker               
          can cause significant changes to be registered, data                        







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