Ex Parte ZAROMB - Page 4




                    Appeal No. 1997-3056                                                                                                                                  
                    Application No. 08/377,966                                                                                                                            


                              MiniKap module has the advantages of a filter with                                                                                          
                              "greater surface area in less space, higher flow rates,                                                                                     
                              and minimal hold up volume... and the multiple end                                                                                          
                              fitting configurations allow the MiniKap filter to be                                                                                       
                              plumed into virtually any system" (see the disclosure                                                                                       
                              statement received 7/10/95, Appendix 8, page B-6 or the                                                                                     
                              newly cited MiniKap 225/500 Microfiltration Modules).  It                                                                                   
                              would have been within the skill of the art to modify USP                                                                                   
                              5,173,264 to use a well known commercially available                                                                                        
                              filtration unit, such as the MiniKap 500 module, to gain                                                                                    
                              the advantages taught above.                                                                                                                
                                        The "MiniKap 500 module" is notoriously well                                                                                      
                              known in the art to have the physical properties/                                                                                           
                              specifications of an effective filtration area of 500                                                                                       
                              square centimeters, a 37 ml hold up volume and up to a                                                                                      
                              300 1/min flow rate at about 23 psi(see Applicant                                                                                           
                              disclose on page 5 lines 3+ of the specification).  It                                                                                      
                              would have been obvious the modified USP 5,173,264                                                                                          
                              incorporating the MiniKap module would have met the                                                                                         
                              claimed physical properties of a throughput of at least                                                                                     
                              100 liters/minute, an effective filtration area of at                                                                                       
                              least 500 square centimeters and a hold up volume of not                                                                                    
                              more than 40 milliliters.                                                                                                                   
                              The Examiner’s obviousness-type double patenting rejections                                                                                 
                    of the other appealed claims are based upon the references and                                                                                        
                    rationale set forth above and further in view of the Electrascan,                                                                                     
                    DeAngelis, Gunasingham, or Heijne references listed earlier in this                                                                                   
                    decision.                                                                                                                                             
                              We refer to the various briefs and answers of record for a                                                                                  
                    complete exposition of the opposing viewpoints expressed by the                                                                                       
                    Appellant and by the Examiner concerning the obviousness-type                                                                                         
                    double patenting rejections before us on this appeal.                                                                                                 

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