Ex parte WILLIAMS et al. - Page 9




              Appeal No. 1998-0318                                                                     Page 9                 
              Application No. 08/539,466                                                                                      


              system includes means for aspirating material from the sample tubes, Hulette evidences                          
              no concern for dealing with micro-samples and the attendant problem of preventing                               
              gouging of the micro-sample tube during insertion of a probe.  The Charlton tube is used in                     
              a centrifuge apparatus, and is tapered for the purposes of providing a reservoir for the                        
              particulate material that moves outwardly during the centrifuge operation (column 1, lines                      
              28-31) and allowing room within the diameter of the envelope of the sample tube for                             
              radiation shielding surrounding this tapered internal portion of the tube (column 2, lines 13-                  
              27).  There would appear to be no reason why one of ordinary skill in the art would have                        
              been motivated to replace the conventionally-shaped sample tube of Hulette, which                               
              provides for optical scanning, with one shaped to accommodate radio-active particulate                          
              material in a centrifuge.                                                                                       

                      As for Cole-Parmer, it is our opinion that it cannot positively be established that any                 
              of the disclosed sample tubes includes a convexly curved interior wall portion.  This being                     
              the case, the rejection fails at the outset, for even if the required suggestion to combine the                 
              teachings were present, the result would not be the structure recited in claim 23.                              
                      Considering the two secondary references collectively, rather than alternatively,                       
              does not alter our conclusion.                                                                                  
                      We therefore will not sustain the Section 103 rejection of independent claim 23 or, it                  
              follows, of claims 24-39, which depend therefrom.                                                               









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