Ex parte COLE - Page 6


            Appeal No. 1998-1672                                                    
            Application No. 08/708,163                                              

            although the specific example at column 43 does not include             
            a pH of from about 9.3 to 9.7, column 24, lines 11-12,                  
            discloses a more preferred amount of from 9.0 to 11.0.  We              
            note that it is not invention to discover optimum or                    
            workable ranges by routine experimentation.  Where general              
            conditions of the appealed claim are disclosed in the prior             
            art, it is not inventive to discover optimum or workable                
            ranges by routine experimentation, and appellants have the              
            burden of proving any criticality.  In re Boesch, 617 F.2d              
            272, 276, 205 USPQ 215, 218-19 (CCPA 1980); In re Aller,                
            220 F.2d 454, 456, 105 USPQ 233, 235 (CCPA 1955).                       
                 Once a prima facie case of obviousness is established              
            by the examiner, as in the present case, the burden shifts              
            to appellant to rebut it.  In re Piasecki, 745 F.2d 1468,               
            1472, 223 USPQ 785, 788 (Fed. Cir. 1984).  A prima facie                
            case of obviousness is rebuttable by proof that the claimed             
            invention possesses unexpectedly advantageous or superior               
            properties.  In re Papesch, 50 CCPA 1084, 1091-92, 315 F.2d             
            381, 386-87, 137 USPQ 43, 47-48 (CCPA 1963).  As rebuttal               
            evidence, Appellant refers to the data on pages 17-20 of                
            this specification.  This data is insufficient to rebut the             
            prima facie case of obviousness for the following reasons.              
                 Rebuttal evidence can be in the form of direct or                  
            indirect comparative testing between the claimed invention              
            and the closest prior art.  In re Merchant, 575 F.2d 865,               
            869, 197 USPQ 785, 788 (CCPA 1978); In re Blondel, 499 F.2d             
            1311, 1317, 182 USPQ 294, 298 (CCPA 1974); In re Swentzel,              
            42 CCPA 757, 763, 219 F.2d 216, 220, 104 USPQ 343, 346                  
            (1955).  In the present case, the data on pages 17-20 is                
            not compared with the closet solution disclosed in                      
            Fujimoto.                                                               

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