Ex parte CHRISTNER et al. - Page 5




                   Appeal No. 1998-1720                                                                                                                             
                   Application No. 08/384,239                                                                                                                       
                            We disagree. As set forth in In re Kotzab, 217 F.3d 1365, 1369-70, 55 USPQ2d                                                            
                   1313, 1316 (Fed. Cir. 2000):                                                                                                                     
                            Most if not all inventions arise from a combination of old elements. [] Thus,                                                           
                            every element of a claimed invention may often be found in the prior art. []                                                            
                            However, identification in the prior art of each individual part claimed is                                                             
                            insufficient to defeat patentability of the whole claimed invention. [] Rather, to                                                      
                            establish obviousness based on a combination of the elements disclosed in                                                               
                            the prior art, there must be some motivation, suggestion or teaching of the                                                             
                            desirability of making the specific combination that was made by the                                                                    
                            applicant.  [citations omitted]                                                                                                         
                            In other words, “[o]ne cannot use hindsight reconstruction to pick and choose                                                           
                   among isolated disclosures in the prior art to deprecate the claimed invention.”  In re Fine,                                                    
                   837 F.2d 1071, 1075, 5 USPQ2d 1596, 1600 (Fed. Cir. 1988).  “[T]here still must be                                                               
                   evidence that ‘a skilled artisan, . . . with no knowledge of the claimed invention, would                                                        
                   select the elements from the cited prior art references for combination in the manner                                                            
                   claimed.’”  Ecolochem Inc. v. Southern California Edison, 227 F.3d 1361, 1375, 56                                                                
                   USPQ2d 1065, 1075-76 (Fed. Cir. 2000).  In our view, that evidence is lacking in the                                                             
                   examiner’s rejection and in the art cited.                                                                                                       
                            Thomas’ focus is on protecting proteases from digestive acids by complexing them                                                        
                   with tannin; Geyer releases and activates the enzyme from the tannin-protease complex                                                            
                   with surfactants (which are expressly excluded from the claimed composition); while Töpfer                                                       
                   releases active enzyme with acetone.  Green, Borello and Tang, on the other hand, teach                                                          

                            2(...continued)                                                                                                                         
                   pages are numbered 1-3, the fourth page is unnumbered, and the fifth, sixth and seventh                                                          
                   pages are numbered 3-5.                                                                                                                          
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