Appeal No. 1998-2010 Application No. 08/542,861 of a similar class to the claimed compounds in a manner which would support enablement of the full scope of the pending claims (Answer, page 5). After evidence or arguments are submitted by the appellants in response to a rejection based on lack of enablement, patentability is determined on the totality of the record, by a preponderance of evidence with due consideration to persuasiveness of the argument. We have carefully studied the arguments and evidence of record. On balance, we believe that the totality of the evidence presented by the examiner and appellants weighs in favor of finding the claimed invention lacks enablement and would require undue experimentation to practice the claimed invention within the full scope of the claims. The rejection of the claims under 35 U.S.C. § 112, first paragraph is affirmed. Improper Markush Group Claims 1, 5, 7-11, and 17-25 stand rejected under the judicial doctrine of being drawn to an improper Markush group. As the rejection of all the claims under 35 U.S.C. § 112, first paragraph has been affirmed and disposes of all the claims on appeal, it is not necessary for us to reach, and we have not considered and do not reach the rejection based on an improper Markush group. Other Issue 14Page: Previous 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 NextLast modified: November 3, 2007