Ex parte VAZQUEZ et al. - Page 14




               Appeal No. 1998-2010                                                                                                 
               Application No. 08/542,861                                                                                           


               of a similar class to the claimed compounds in a manner which would support enablement                               
               of the full scope of the pending claims (Answer, page 5).                                                            
                       After evidence or arguments are submitted by the appellants in response to a                                 
               rejection based on lack of enablement, patentability is determined on the totality of the                            
               record, by a preponderance of evidence with due consideration to persuasiveness of the                               
               argument.  We have carefully studied the arguments and evidence of record.  On balance,                              
               we believe that the totality of the evidence presented by the examiner and appellants                                
               weighs in favor of finding the claimed invention lacks enablement and would require undue                            
               experimentation to practice the claimed invention within the full scope of the claims.  The                          
               rejection of the claims under 35 U.S.C. § 112, first paragraph is affirmed.                                          


               Improper Markush Group                                                                                               
                       Claims 1, 5, 7-11, and 17-25 stand rejected under the judicial doctrine of being                             
               drawn to an improper Markush group.   As the rejection of all the claims under 35 U.S.C. §                           
               112, first paragraph has been affirmed and disposes of all the claims on appeal, it is not                           
               necessary for us to reach, and we have not considered and do not reach the rejection                                 
               based on an improper Markush group.                                                                                  
               Other Issue                                                                                                          




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