Ex parte VAZQUEZ et al. - Page 7




               Appeal No. 1998-2010                                                                                                 
               Application No. 08/542,861                                                                                           


               Example 4, and page 68, lines 26-37, describes the procedure one of ordinary skill in the                            
               art can use to prepare sulfamoyl halides.  The specification, pages 55, 56, example 8 and                            
               pages 58-59, appears to support methods of preparing succinic acid (succinate)                                       
               derivatives.                                                                                                         
                       The examiner additionally argues that appellants have failed to show how to                                  
               selectively prepare hetero rings at one ring position versus the many positions possible for                         
               ring systems that include mono-, bi- and tri- cyclic rings.   Answer, page 6.   The                                  
               specification, page 63, however, states that utilizing the procedures set forth therein, the                         
               compounds of Tables 4-14 can be prepared and that utilizing the intermediates of                                     
               examples 1-13 according to the procedures of example 14, the compounds shown in                                      
               tables 4-16 could be prepared.   The appellants further argue that a person skilled in the art                       

               would recognize where and how the heteroatom containing rings could be attached to the                               
               backbone structure set forth in the disclosure.   Brief, page 10.   Appellants reference                             
               several patents and general chemistry reference materials to support this position.  Brief,                          
               pages 10-14.  The examiner responds to this argument with the statement (Answer, pages                               
               6-7):                                                                                                                
                       The fact that rings included within the instant scope may be known rings as                                  
                       appellants urge by referring to various organic textbooks, is not the issue but                              
                       rather if the specification as filed provides sufficient enablement to make                                  
                       hetero-substituted final products of the scope being claimed. ... While the                                  
                       generalized routes in the specification may provide sufficient guidelines for                                
                       making final products listed in the tables, the                                                              

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