Ex parte LINDOR - Page 3




              Appeal No. 1998-2267                                                                                         
              Application 08/339,084                                                                                       



              the examiner's reasoning in support of the rejection, and to the appellant's Brief for the                   
              appellant's arguments thereagainst.  As a consequence of our review, we make the                             
              determinations which follow.                                                                                 
              35 U.S.C. § 103                                                                                              
                     Claims 1-8 stand rejected under 35 U.S.C. § 103 over Podda in view of Shironaga.                      
                     In rejecting claims under 35 U.S.C. § 103, the examiner bears the initial burden of                   
              presenting a prima facie case of obviousness.  See In re Rijckaert, 9 F.3d 1531, 1532, 28                    
              USPQ2d 1955, 1956 (Fed. Cir. 1993).   A prima facie case of obviousness is established                       
              when the teachings from the prior art itself would appear to have suggested the claimed                      
              subject matter to a person of ordinary skill in the art.  In re Bell, 991 F.2d 781, 783, 26                  
              USPQ2d 1529, 1531 (Fed. Cir. 1993).  An obviousness analysis requires that the prior art                     
              both suggest the claimed subject matter and reveal a reasonable expectation of success                       
              to one reasonably skilled in the art.   In re Vaeck, 947 F.2d 488, 493, 20 USPQ2d 1438,                      
              1442  (Fed. Cir. 1991).    With this as background, we analyze the prior art applied by the                  
              examiner in the rejection of the claims on appeal.                                                           
                     Nonalcoholic steatohepatitis (NASH) is a liver condition which involves the                           
              development of histologic changes in the liver which are comparable to those induced by                      
              excessive alcohol intake, but in the absence of alcohol.  NASH is commonly associated                        
              with hyperlipidemia, obesity, and type II diabetes mellitus.  Specification, page 1.                         

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