Appeal No. 1998-2267 Application 08/339,084 the examiner's reasoning in support of the rejection, and to the appellant's Brief for the appellant's arguments thereagainst. As a consequence of our review, we make the determinations which follow. 35 U.S.C. § 103 Claims 1-8 stand rejected under 35 U.S.C. § 103 over Podda in view of Shironaga. In rejecting claims under 35 U.S.C. § 103, the examiner bears the initial burden of presenting a prima facie case of obviousness. See In re Rijckaert, 9 F.3d 1531, 1532, 28 USPQ2d 1955, 1956 (Fed. Cir. 1993). A prima facie case of obviousness is established when the teachings from the prior art itself would appear to have suggested the claimed subject matter to a person of ordinary skill in the art. In re Bell, 991 F.2d 781, 783, 26 USPQ2d 1529, 1531 (Fed. Cir. 1993). An obviousness analysis requires that the prior art both suggest the claimed subject matter and reveal a reasonable expectation of success to one reasonably skilled in the art. In re Vaeck, 947 F.2d 488, 493, 20 USPQ2d 1438, 1442 (Fed. Cir. 1991). With this as background, we analyze the prior art applied by the examiner in the rejection of the claims on appeal. Nonalcoholic steatohepatitis (NASH) is a liver condition which involves the development of histologic changes in the liver which are comparable to those induced by excessive alcohol intake, but in the absence of alcohol. NASH is commonly associated with hyperlipidemia, obesity, and type II diabetes mellitus. Specification, page 1. 3Page: Previous 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007