Appeal No. 1998-3050 Application No. 08/586,116 a pipette tip for use in conjunction with a pipettor, the pipette tip having first and second ends and bearing the substrate which comprises a separate substrate strip with distinct reactants in a spaced-apart relation, the substrate strip disposed longitudinally within the pipette tip, wherein the pipette tip is in combination with means for aspirating the sample through the first end of the pipette tip by a pipettor acting on the second end of the pipette tip, so that contact is provided between the reactants and the sample on the substrate strip. The examiner relies upon the following references as evidence of obviousness: Elkins 4,308,028 Dec. 29, 1981 Ebersole et al. (Ebersole) 4,806,313 Feb. 21, 1989 Wainright et al. (Wainright) 5,171,537 Dec. 15, 1992 Appellants' claimed invention is directed to a combination comprising a pipette tip having a substrate strip disposed longitudinally therein. The substrate strip contains distinct reactants in a spaced-apart relation, which strip comes in contact with liquid sample that is aspirated into the pipette tip. The sample is analyzed by its reaction with the distinct reactants on the substrate strip. Appealed claims 77-87 stand rejected under 35 U.S.C. § 103 as being unpatentable over Wainright in view of Ebersole and Elkins. Appellants submit at page 4 of the Brief that "[a]s to the rejections of claims 77-87, it is applicants' intention that the -2-Page: Previous 1 2 3 4 5 6 NextLast modified: November 3, 2007