Ex parte LAWRENCE et al. - Page 5



                 Appeal No.  1999-0123                                                                                    
                 Application No. 08/406,239                                                                               

                         In this case the examiner failed to analyze the claimed invention with                           
                 reference to the factors set forth in Wands.  In addition, the examiner failed to                        
                 provide any support upon which to base his opinion that undue experimentation                            
                 would be required to practice the invention.  Instead, the examiner merely provides                      
                 conclusory statements, such as “a number of types [sic] of hydrolytic enzymes are                        
                 contemplated but the specification is not enabling for all of them.  Many would not                      
                 likely work in the claimed invention…” and “inhibitors are contemplated but the                          
                 specification does not teach how to perform the assays for all the inhibitors”                           
                 (Answer, page 11).                                                                                       
                         As set forth in In re Marzocchi, 439 F.2d 220, 223, 169 USPQ 367, 369                            
                 (CCPA 1971) it is “incumbent upon the Patent Office, whenever a rejection on this                        
                 basis is made, to explain why it doubts the truth or accuracy of any statement in a                      
                 supporting disclosure and to back up assertions of its own with acceptable                               
                 evidence or reasoning which is inconsistent with the contested statement.”  On this                      
                 record the examiner has merely asserted that due to the large number of                                  
                 embodiments encompassed by the claimed invention, many would not likely work in                          
                 the claimed invention.  In addition, with regard to the examiner’s concern that the                      
                 claimed invention includes inoperative embodiments, we direct the examiner’s                             
                 attention to Atlas Powder Co. v. E.I. DuPont De Nemours & Co., 750 F.2d 1569,                            
                 1576-77, 224 USPQ 409, 414 (Fed. Cir. 1984):                                                             
                         Even if some of the claimed combinations were inoperative, the                                   
                         claims are not necessarily invalid.  “It is not a function of the claims to                      
                         specifically exclude ... possible inoperative substances ....”  In re Dinh-                      

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