Ex Parte WOZNEY et al - Page 2




             Appeal No.  1999-1280                                                                              
             Application No.  08/379,813                                                                        

                   Claims 1 and 6 are representative of the claims on appeal and read as follows:               
                       1. A method for treatment of a supraalveolar periodontal lesion or defect                
                          consisting essentially of administering to a site of said supraalveolar               
                          periodontal lesion or defect a pharmaceutically acceptable composition                
                          containing one or more purified or recombinant bone morphogenetic                     
                          protein (BMPs) in an amount sufficient to cause regeneration of alveolar              
                          bone at the site of said lesion or defect in both a vertical and horizontal           
                          direction.                                                                            
                       6. A method for treatment of a supraalveolar periodontal lesion or defect                
                          according to claim 1, wherein the composition comprises recombinant                   
                          human BMP-12 and recombinant human BMP-2 in a suitable carrier.                       
                   The references relied on by the examiner are:                                                
             Antoniades et al. (Antoniades)         5,124,316                 Jun.  23, 1992                   
             Bentz et al. (Bentz)                  5,393,739                  Feb. 28, 1995                    
                                             GROUNDS OF REJECTION                                               
                   Claims 1-33 stand rejected under 35 U.S.C. § 112, first paragraph, as the                    
             specification fails to provide an enabling description of all Bone Morphogenetic Proteins          
             (BMPs).1                                                                                           
                   Claims 1, 2, 7-13, 18-24, and 29-33 stand rejected under 35 U.S.C. § 102 as                  
             being anticipated by Antoniades.                                                                   
                   Claims 1-33 stand rejected under 35 U.S.C. § 103 as being unpatentable over                  
             Bentz.                                                                                             



                                                                                                               
             1 We note the rejection of claims 1-33 is directly connected and relates to the objection          
             to the specification.  In re Hengehold, 440 F.2d 1395, 1403-1404, 169 USPQ 473, 479-               
             480 (CCPA 1971).                                                                                   
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