Appeal No. 1999-1313 Application 08/448,097 composition or device, or carry out the claimed process; and (2) whether the prior art would also have revealed that in so making or carrying out, those of ordinary skill would have a reasonable expectation of success. Both the suggestion and the reasonable expectation of success must be founded in the prior art, not in the applicant’s disclosure. In re Vaeck, 947 F.2d. 488, 495, 20 USPQ2d 1438, 1442 (Fed. Cir. 1991). The examiner must show that some objective teaching or suggestion in the applied prior art, or knowledge generally available in the art, would have led one of ordinary skill in the art to the claimed invention. Pro-Mold & Toll Co. v. Great Lakes Plastics, Inc., 75 F. 3d 1568, 1573, 37 USPQ2d 1626, 1630 (Fed. Cir. 1996). In reaching our decision in this appeal, we have given careful consideration to appellants’ specification and claims and to the respective positions articulated by appellants and the examiner. We make reference to the Examiner’s Answer mailed June 24, 1998 (Paper No. 16 ) for the examiner’s reasoning in support of the rejection, and to the Appeal Brief, received March 2, 1998 (Paper No. 15), and Reply Brief, received October 29, 1998 (Paper No. 18) for appellants’ arguments against the rejection. We have also carefully considered the references cited by the examiner. In rejecting the appealed claims, the examiner characterizes Granoff as teaching the purification of a 28 KD protein from H. influenzae, termed P4, which is the same as appellant’s protein “e”. The examiner cites Deich as teaching the cloning and 4Page: Previous 1 2 3 4 5 6 7 8 NextLast modified: November 3, 2007