SHIOKAWA et al. V. MAIENFISCH et al. - Page 50




                same and separate patentable inventions.  Indeed, Shiokawa erroneously states the facts and reasoning                    

                set forth in Fujikawa.  In Fujikawa, Fujikawa filed a motion to add a narrow subgenus count and it                       

                was Wattanasin’s disclosure that did not sufficiently describe the subject matter of the proposed                        

                count.  The court made no mention of an estoppel theory in determining that Wattanasin’s disclosure                      

                lacked adequate written description for the proposed subgenus count.  It does not stand to reason that                   

                the court meant to imply that Fujikawa’s motion estopped Wattanasin from asserting adequate written                      

                descriptive support for the proposed subgenus.                                                                           



                                2.      Dr. Zielger’s Testimony Does Not Establish Presence of 1,3,5-oxadiazine in                       
                                        Final Product of Example 5                                                                       

                        Shiokawa contends that Dr. Ziegler, Maienfisch’s expert, conceded that a 1,3,5-oxadiazine                        

                should be considered among the products formed in the reaction mixture of example 5.  (Paper No. 81,                     

                p. 10 and SX 2086).  While it appears that Dr. Ziegler could not rule out the possibility that a 1,3,5-                  

                oxadiazine could be formed using the nitroguanidine and paraformaldehyde of example 5, it is not clear                   

                that Dr. Ziegler admits that a 1,3,5-oxadiazine would be present in the final product of example 5.                      

                Specifically, Dr. Ziegler’s depiction of the products of example 5 (SX 2086) appears directed to                         

                example 5 of the ‘146 patent with the methoxyamine hydrochloride (amine reactant) being specifically                     

                omitted from the reaction mixture.  Similarly, the question asked of Dr. Ziegler during his cross-                       

                examination included the statement “the 1,3,5-oxadiazine was one of the possible products following                      

                example 5 but omitting the amine reactant.”  While the omission of the amine reactant may result in the                  

                formation of the 1,3,5-oxadiazine the focus of example 5 is a reaction where methoxyamine                                


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