SHIOKAWA et al. V. MAIENFISCH et al. - Page 59




                     surprising or unexpected.  That two 1,3,5-oxadiazines, S19 and S20, were merely equivalent or in                                                                  

                     some instances less effective than compounds that do not appear to be specifically depicted or explicitly                                                         

                     identified by the ‘146 patent does not alter our conclusion.  Specifically, Maienfisch has provided                                                               

                     convincing evidance that its claimed 1,3,5-oxadiazines would not have been obvious to one skilled in                                                              

                     the art given the teachings of the JP ‘943 reference.                                                                                                             



                                E.         Shiokawa Preliminary Motion 13 to Suppress Maienfisch’s Exhibit 1001                                                                        

                                Shiokawa Preliminary Motion 13 requests that the Declaration of Dr. Fredrick E. Ziegler,                                                               

                     Maienfisch Exhibit 1001, be suppressed.  According to Shiokawa, the purpose of Dr. Zielger’s                                                                      

                     declaration was to support Maienfisch’s arguments in its first and only preliminary motion.  (Shiokawa                                                            

                     Preliminary Motion 13, Paper No. 102, p. 15).  Shiokawa alleges that Dr. Ziegler has demonstrated a                                                               

                     level of skill in the relevant field of heterocyclic chemistry that falls below that of one of ordinary skill in                                                  

                     the art.                                                                                                                                                          

                                In rendering our decision on preliminary motions, we have not found it necessary to rely upon                                                          

                     the declaration testimony of Dr. Ziegler.  Accordingly, the motion to suppress Dr. Ziegler’s declaration                                                          

                     testimony (MX 1001) is dismissed as moot.                                                                                                                         



                                F.         Shiokawa Preliminary Motion 14 to Suppress Maienfisch’s Exhibits 1005, 1006 and                                                             
                                           Paragraphs 48-49 of Exhibit 1001                                                                                                            

                                Shiokawa Preliminary Motion 14 requests that Maienfisch Exhibits 1005 and 1006 and                                                                     

                     paragraphs 48 and 49 of Maienfisch Exhibit 1001, the Declaration of Dr. Fredrick E. Ziegler, be                                                                   


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