VISSER et al v. HOFVANDER et al - Page 121




          Interference 103,579                                                        
          sequences each party’s claims describe for insertion into the               
          genome of the potato plant in the antisense direction.                      
               Visser has established at least that the parties’ claims               
          prima facie are drawn to separate patentable inventions based on            
          their comparatively separate and distinct chemical structures.              
          Thus, the burden has been shifted to Hofvander to show that the             
          inventions the parties claim are directed to the same patentable            
          invention.  Hofvander has not satisfied its burden.                         
               Contrary to the views expressed in Hofvander’s Main                    
          Brief at Final Hearing (HB 1, first para.), we conclude that                
          the invention defined by Hofvander’s claims designated as                   
          corresponding to the count and the invention defined by Visser’s            
          claims designated as corresponding to the count are not directed            
          to obtaining amylose-free starch by suppressing/inhibiting the              
          GBSS gene by use of any effective antisense construct.  Rather,             
          we conclude that the invention of Hofvander’s claims designated             
          as corresponding to the count and the invention of Visser’s                 
          claims designated as corresponding to the count are directed to             
          very specific antisense constructs and methods of using very                
          specific antisense constructs to obtain amylose-free starch by              
          suppressing/inhibiting the GBSS gene.  None of Hofvander’s or               
          Visser’s claims designated as corresponding to the count are                
          generally directed to the successful use of antisense technology            
          to suppress/inhibit expression of the GBSS gene in potato plants.           
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