HUANG et al. V. PRASIT et al. - Page 21




          art would have reasonably doubted the utility asserted.  In re              
          Cortright,                                                                  
          165 F.3d 1353, 1357, 49 USPQ2d 1464, 1466 (Fed. Cir. 1999).                 
          Therefore, Huang has the burden to show by a preponderance of               
          the evidence that one having ordinary skill in the art would                
          have doubted Prasit's assertion that the compounds it claims                
          are useful as COX-2 inhibitors.  We hold that Huang has not                 
          met its burden.                                                             
               Huang argues that Merck should be bound by the testimony               
          of its witnesses, Dr. Chan and Dr. Riendeau, given in prior                 
          interferences '845 and '873 to which Merck was a party.                     
          According to Huang, the testimony is an admission by Merck                  
          that the compounds of its '931 application lack utility and                 
          enablement.                                                                 
               It is proper for Huang to rely upon the testimony given                
          by Dr. Chan and Dr. Riendeau in the '845 and '873                           
          interferences.                                                              
          37 CFR § 1.683(a).  However, a review of the entire testimony               
          of                                                                          
          Dr. Chan and Dr. Riendeau indicates that their testimony                    
          concerning the predictability of COX-2 inhibition from in                   
          vitro testing was directed to the specific compounds described              



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