Ex parte GANTE et al. - Page 6


                 Appeal No.  2000-0600                                                           Page 6                   
                 Application No.  08/642,268                                                                              
                 that the specification makes reference to a number of disorders, including, “(but …                      
                 not limited to) thromboses,[ ]osteolytic disorders, kidney failure [and] antitumor                       
                 agents.”  However, the examiner finds (Answer, pages 5-6) that the “nature of                            
                 testing relied on in the specification does not appear to be art-recognized for                          
                 treating all such disorders.”  In this regard, the examiner makes reference (Answer,                     
                 page 6) to two prior art references – Muller and Smith.  However, as set forth on                        
                 page 3 of the Answer, “[n]o prior art is relied upon by the examiner in the rejection of                 
                 the claims under appeal.”  As set forth in In re Hoch, 428 F.2d 1341, 1342 n.3, 166                      
                 USPQ 406, 407 n.3 (CCPA 1970) (“[w]here a reference is relied on to support a                            
                 rejection, whether or not in a ‘minor capacity,’ there would appear to be no excuse                      
                 for not positively including the reference in the statement of the rejection”).                          
                 Accordingly, the examiner’s reliance on Muller and Smith is in error.                                    
                         Notwithstanding the examiner’s error, appellants responded to the                                
                 examiner’s argument (Reply Brief, page 4), therefore, we will consider the                               
                 references to the extent that the examiner and appellants have relied on them.  For                      
                 emphasis, the following quote reproduces in full the examiner’s position relative to                     
                 the cited references (Answer, page 6), “[a]t best,[ ]Muller, provided in an earlier                      
                 action, suggests a correlation exists for the treatment of thrombosis-see second [to                     
                 the] last paragraph on p.[ ]113.  Note also Smith cited in the specification,[ ]p.[ ]4, for              
                 an example of a ligand binding assay that can be used does not make such                                 
                 assertions.  See page 12270.”                                                                            
                         While we find the examiner’s point less than clear, we find appellants’                          
                 response compelling.  According to appellants’ (Reply Brief, page 4):                                    






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