Ex parte ESTEP et al. - Page 6




          Appeal No. 2000-0965                                                        
          Application No. 08/927,465                                                  


          so                                                                          
          doing, the Examiner is expected to make the factual                         
          determinations set forth in Graham v. John Deere Co., 383 U.S.              
          1,                                                                          
          17, 148 USPQ 459, 467 (1966), and to provide a reason why one               
          having ordinary skill in the pertinent art would have been led              
          to                                                                          
          modify the prior art or to combine prior art references to                  
          arrive                                                                      
          at the claimed invention.  Such reason must stem from some                  
          teaching, suggestion or implication in the prior art as a                   
          whole                                                                       
          or knowledge generally available to one having ordinary skill               
          in                                                                          
          the art.  Uniroyal, Inc. v. Rudkin-Wiley Corp., 837 F.2d 1044,              
          1051, 5 USPQ2d 1434, 1438 (Fed. Cir.), cert. denied, 488 U.S.               
          825                                                                         
          (1988); Ashland Oil, Inc. v. Delta Resins & Refractories,                   
          Inc.,                                                                       
          776 F.2d 281, 293, 227 USPQ 657, 664 (Fed. Cir. 1985), cert.                
          denied, 475 U.S. 1017 (1986); ACS Hosp. Sys., Inc. v.                       
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