Ex Parte ESTES et al - Page 3



             Appeal No. 2000-1559                                                              Page 3               
             Application No. 07/911,593                                                                             
                    (b)  orally administering at least 1 x 102 PFU of a rotavirus vaccine to said                   
             nursing mother,                                                                                        
                    wherein said steps (a) and (b) may be performed in any order.                                   


                                             The Prior Art References                                               
                    In rejecting the appealed claims on prior art grounds, the examiner relies on the               
             following references:                                                                                  
             Zygraich                          4,341,763                   Jul.   27, 1982                          
             Welter et a. (Welter)             5,147,639                   Sep. 15, 1992                            
             Ward                              5,474,773                   Dec. 12, 1995                            
             Smith et al. (Smith)                                                                                   
             European Patent Application       0 251 467 A2                Jan.   7, 1988                           
             Ijaz et al. (Ijaz), "Effect of different routes of immunization with bovine rotavirus on               
             lactogenic antibody response in mice," Antiviral Research, Vol. 8, pp. 283-298 (1987)                  
             Estes et al. (Estes), "Synthesis and Immunogenicity of the Rotavirus Major Capsid                      
             Antigen Using a Baculovirus Expression System," Journal of Virology, pp. 1488-1494                     
             (May 1987)                                                                                             

                                                  The Rejections                                                    
                    The appealed claims stand rejected as follows:                                                  
                    (1)  Claims 5, 6, 8 through 13, 15 through 21, and 29 through 31 under 35 U.S.C.                
                    § 102(b) as anticipated by Zygraich;                                                            
                    (2)  Claims 5, 6, 8, 9, 11, 12, 19, 21, 22, 24, 29, and 31 under 35 U.S.C. § 102(b)             
                    as anticipated by Ijaz;                                                                         
                    (3)  Claims 5 through 7, 12, 13, and 19 through 27 under 35 U.S.C. § 102(e) as                  
                    anticipated by Ward;                                                                            
                    (4)  Claims 5 through 27, 29 through 32, 34 through 37, and 39 through 42 under                 
                    35 U.S.C. § 103(a) as unpatentable "over Zygraich and Ijaz, in view of Estes or                 
                    Smith;" and                                                                                     
                    (5)  Claims 5, 6, 8 through 13, 15 through 21, and 29 through 31 under 35 U.S.C.                





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