Ex Parte ESTES et al - Page 5



             Appeal No. 2000-1559                                                              Page 5               
             Application No. 07/911,593                                                                             
                                                                                                                   
             1988).  Here, the examiner has not established that Zygraich discloses a virus                         
             "classified in a rotavirus serotype which includes at least one human rotavirus" as                    
             recited in each claim on appeal.  Accordingly, the examiner has not established a prima                
             facie case of anticipation of applicants' claims under 35 U.S.C. § 102(b) based on the                 
             cited Zygraich patent.                                                                                 
                    Applicants point out, and the examiner does not deny, that Zygraich describes                   
             preparation of bovine rotavirus strain RIT 4237 in Example 1 (column 3, line 51 through                
             column 4, line 8).  See the Appeal Brief, page 5, lines 9 through 12.  This can also be                
             seen on comparing Zygraich, Example 1 with Zissis et al., page 1061, last paragraph;                   
             and page 1062, first two paragraphs.  Ward discloses that (1)  human rotaviruses may                   
             be divided into six serotypes, i.e., serotypes 1-4 and 8-9, based on differences in the                
             VP4 and VP7 proteins (column 2, lines 14 through 16); and (2)  RIT 4237 bovine strain                  
             rotavirus is classified as serotype 6 (column 3, lines 40 and 41).  In our judgment,                   
             therefore, the examiner has not presented adequate reason to believe that bovine                       
             rotavirus strain RIT 4237, described in Example 1 of Zygraich, is "classified in a                     
             rotavirus serotype which includes at least one human rotavirus."2                                      
                    The rejection of claims 5, 6, 8 through 13, 15 through 21, and 29 through 31                    
             under 35 U.S.C. § 102(b) as anticipated by Zygraich is reversed.                                       


                                                        Ijaz                                                        
                    Again, for a prior art reference to anticipate in terms of 35 U.S.C. § 102, every               

                    2   The examiner's position to the contrary, notwithstanding, page 1066, third complete paragraph
             of Zissis et al. describes classification of rotaviruses by subgroup, not serotype.                    





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