Ex Parte WEST - Page 6


                 Appeal No.  2000-1909                                                        Page 6                    
                 Application No.  08/790,528                                                                            

                        The rejection relies upon Beringer for teaching “the standard methods of                        
                 making tablets that are encased by gum, as well as methods of making gum                               
                 encased by a chewable tablet for the administration of a pharmaceutically active                       
                 agent.”  Id. at 7.  Cherukuri is cited for teaching chewing gums that incorporate                      
                 antacids, as well as disclosing “the many sweeteners, and flavoring agents                             
                 useful in the production of a medicated gum.”  Id.  The rejection concludes that                       
                        [i]t would have been  obvious to one of ordinary skill in the art at the                        
                        time the invention was made to have added an antiflatulent to the                               
                        chewable tablets of Caldwell, Gottwald, France or Upson, as both                                
                        the antiflatulents and the combinations thereof with antacids and                               
                        acid production inhibitors in a chewable form were well known in                                
                        the art at the time the invention was made for the treatment of                                 
                        gastroesophageal disorders, as listed by Drug Facts and                                         
                        Comparisons.  It would have further been obvious to have added                                  
                        an integral chewing gum through the methods of Beringer or                                      
                        Cherukuri, as such multi zone delivery compositions were well                                   
                        known in the art and they allowed the incorporation of different                                
                        pharmaceuticals.                                                                                
                 Id. at 7-8.                                                                                            







                        Appellant argues that the references relied upon by the examiner do not                         
                 provide any motivation to provide a chewable tablet containing an antacid, an                          
                 anti-gas agent and a H-2 receptor antagonist integral with a chewing gum matrix.                       
                 We agree.                                                                                              








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