Ex Parte TACKETT - Page 3


                 Appeal No. 2001-1925                                                           Page 3                    
                 Application No. 08/677,838                                                                               



                         Four examples are presented.  Examples 1, 2 and 4 are drawn to                                   
                 application of the solution to wrinkles, and Example 3 is drawn to the application                       
                 of the solution to an age spot.  Examples 2 and 4 have accompanying pictures,                            
                 which, according to the specification, demonstrates the reduction in wrinkles.                           
                 See id. at 16-20.  In addition, the specification states in Example 1 that use of                        
                 the nuclease solution “resulted in the reduction of the subject’s wrinkles,” id. at                      
                 18, and in Example 3, states that “the method results in the reduction of                                
                 discoloration spots on humans,” id. at 19.                                                               
                                                     DISCUSSION                                                           
                         Claim 1 stands rejected under 35 U.S.C. § 112, first paragraph, on the                           
                 grounds that the specification fails to adequately teach how to make and/or use                          
                 the claimed invention, i.e., fails to provide an enabling disclosure.                                    
                         The rejection focuses on the portions of the specification that explain the                      
                 purported mechanism of how the nuclease solution may reduce the appearance                               
                 of wrinkles and age spots.  See Examiner’s Answer, pages 3-7.  However, “it is                           
                 axiomatic that an inventor need not comprehend the scientific principles on                              
                 which the practical effectiveness of his invention rests.”  Fromson v. Advance                           
                 Offset Plate, Inc., 720 F.2d 1565, 1570, 219 USPQ 1137, 1140 (Fed. Cir. 1983);                           
                 see also In re Storrs, 245 F.2d 474, 478, 114 USPQ 293, 297 (CCPA 1957) (“It                             
                 is well established that an applicant for patent need not understand the theory of                       
                 operation of [his] invention.”)                                                                          







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